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Clinical Research Fellow in Respiratory Viral Infections

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Imperial College London Clinical Research Fellow in Respiratory Viral Infections

The closing date is 29 November 2026

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Job summary

We are looking for a highly motivated clinician in training (Internal Medicine/Specialty Registrar Grade or equivalent) with a strong interest in infectious diseases and their prevention to investigate immunity in clinical volunteer studies involving rhinovirus and RSV controlled human infection. You will be part of a multi-disciplinary team focusing on human immunity against respiratory viral infections using exciting and unique studies designs alongside cutting-edge laboratory techniques.

You will join a dynamic group of clinical fellows, research nurses and scientists led by Prof Chris Chiu (www.imperial.ac.uk/people/c.chiu)in the Department of Infectious Disease, to characterise the response to respiratory viruses in older adults. This will accelerate the development of improved prophylactic interventions respiratory viruses, while providing you with unparalleled experience in translational research, experimental medicine and laboratory analyses.

Main duties of the job

  • You will work closely with research nurses, clinical programme manager, other clinical fellows and laboratory scientists to set up and implement human challenge studies to identify determinants of susceptibility and protection against rhinovirus and RSV in older adult volunteers.
  • You will manage the clinical studies, working with research nurses and other clinicians to recruit and screen and care for volunteers, administer virus, and obtain samples.

About us

Welcome to Imperial, a global top ten university where scientific imagination leads to world-changing impact. Join us and be part of something bigger. From global health to climate change, AI to business leadership, we navigate some of the world's toughest challenges. Whatever your role, your contribution will have a lasting impact. As a member of our vibrant community of 22,000 students and 8,000 staff, you'll collaborate with passionate minds across nine London campuses and a global network. This is your chance to help shape the future. We hope you'll join us at Imperial.

Details

Date posted

02 November 2026

Pay scheme

Other

Salary

£55,355 to £67,235 a year

Contract

Fixed term

Duration

24 months

Working pattern

Full-time

Reference number

MED06020

Job locations

Du Cane Rd, London W12 0NN

London

W12 0NN

United Kingdom


Job description

Job responsibilities

We anticipate the successful applicant will take up this position in February/March 2027. You will hold an honorary contract with the appropriate NHS Trusts and be expected to take on clinical responsibilities appropriate to your level of experience expertise, with training in study-specific areas provided:

Clinical study delivery:

Assist with the setup and day-to-day management and delivery of respiratory virus human challenge studies.

Assist with recruitment and screening of volunteers

Collation, review and sign-off of clinical investigations and other documents for eligibility assessment of study participants.

Provide direct clinical care to study participants admitted for respiratory virus challenge, working with research nurses and study PIs.

Support delivery of other clinical studies (including trials) within Prof Chius group.

Acting as a point of contact for study participants to provide clinical advice and care before, during and after challenge, under the supervision of the study PI.

Co-ordinate the development of study protocols and associated study documentation.

Prepare safety reports and briefings for the data safety monitoring committee.

Ensure adherence to the study protocols and compliance with regulatory requirements.

Work with the rest of the clinical team, in particular the lead research nurse and clinical project manager, to ensure all clinical research conducted is compliant with Good Clinical Practice.

Academic development, training and supervision:

Participate in the analysis of immune responses using cellular and molecular immunology techniques if desired and as appropriate.

Training of study associated personnel.

Troubleshooting issues while maintaining and developing good relationships with researchers and clinicians associated with the study in a variety of different settings.

Identifying and developing further research themes which may be developed within the studies

All staff are expected to contribute to the administrative work of the study coordinated through the project manager and study PIs. The post holder will need to carry out any other reasonable duties as required by the study PI, which are likely to increase their breadth of research experience.

Job description

Job responsibilities

We anticipate the successful applicant will take up this position in February/March 2027. You will hold an honorary contract with the appropriate NHS Trusts and be expected to take on clinical responsibilities appropriate to your level of experience expertise, with training in study-specific areas provided:

Clinical study delivery:

Assist with the setup and day-to-day management and delivery of respiratory virus human challenge studies.

Assist with recruitment and screening of volunteers

Collation, review and sign-off of clinical investigations and other documents for eligibility assessment of study participants.

Provide direct clinical care to study participants admitted for respiratory virus challenge, working with research nurses and study PIs.

Support delivery of other clinical studies (including trials) within Prof Chius group.

Acting as a point of contact for study participants to provide clinical advice and care before, during and after challenge, under the supervision of the study PI.

Co-ordinate the development of study protocols and associated study documentation.

Prepare safety reports and briefings for the data safety monitoring committee.

Ensure adherence to the study protocols and compliance with regulatory requirements.

Work with the rest of the clinical team, in particular the lead research nurse and clinical project manager, to ensure all clinical research conducted is compliant with Good Clinical Practice.

Academic development, training and supervision:

Participate in the analysis of immune responses using cellular and molecular immunology techniques if desired and as appropriate.

Training of study associated personnel.

Troubleshooting issues while maintaining and developing good relationships with researchers and clinicians associated with the study in a variety of different settings.

Identifying and developing further research themes which may be developed within the studies

All staff are expected to contribute to the administrative work of the study coordinated through the project manager and study PIs. The post holder will need to carry out any other reasonable duties as required by the study PI, which are likely to increase their breadth of research experience.

Person Specification

Qualifications

Essential

  • Medical degree with GMC registration.

Desirable

  • Membership of the Royal College of Physicians or equivalent.

Experience

Essential

  • Experience in management of general medical problems, medical emergencies and respiratory infections.
  • Demonstrated ability to work collaboratively with other clinicians, nurses and others.

Desirable

  • Knowledge of respiratory infections and current developments in the field.
  • Knowledge of research methods and statistical procedures.
  • Practical experience of clinical studies or trials.
  • Experience of the supervision or training of colleagues.
  • Experience of presenting to specialist and non-specialist audiences
  • Evidence of teaching and teaching support.
  • Familiarity with Good Clinical Practice and governance of clinical studies.
  • Previous research experience in infectious diseases, virology or immunology.

Person Specification

Qualifications

Essential

  • Medical degree with GMC registration.

Desirable

  • Membership of the Royal College of Physicians or equivalent.

Experience

Essential

  • Experience in management of general medical problems, medical emergencies and respiratory infections.
  • Demonstrated ability to work collaboratively with other clinicians, nurses and others.

Desirable

  • Knowledge of respiratory infections and current developments in the field.
  • Knowledge of research methods and statistical procedures.
  • Practical experience of clinical studies or trials.
  • Experience of the supervision or training of colleagues.
  • Experience of presenting to specialist and non-specialist audiences
  • Evidence of teaching and teaching support.
  • Familiarity with Good Clinical Practice and governance of clinical studies.
  • Previous research experience in infectious diseases, virology or immunology.

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Additional information

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Employer details

Employer name

Imperial College London

Address

Du Cane Rd, London W12 0NN

London

W12 0NN

United Kingdom


Employer's website

https://www.imperial.ac.uk/ (Opens in a new tab)

Employer details

Employer name

Imperial College London

Address

Du Cane Rd, London W12 0NN

London

W12 0NN

United Kingdom


Employer's website

https://www.imperial.ac.uk/ (Opens in a new tab)

Employer contact details

For questions about the job, contact:

Recruitment Advisor

Recruitment Hub

[email protected]

Details

Date posted

02 November 2026

Pay scheme

Other

Salary

£55,355 to £67,235 a year

Contract

Fixed term

Duration

24 months

Working pattern

Full-time

Reference number

MED06020

Job locations

Du Cane Rd, London W12 0NN

London

W12 0NN

United Kingdom


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